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Introduction: In December 2019, a novel Coronavirus disease 2019 (COVID-19) was discovered and spread rapidly worldwide. The virus spared no country in its contagiousness. The most common clinical manifestations are respiratory symptoms;but COVID-19 may induce arrhythmias, myocardial infarction, heart failure, and other cardiovascular diseases due to the systemic inflammatory response coupled with localized vascular inflammation. The study aims to provide knowledge about the clinical profile, cardiovascular complications, and clinical outcomes among adult COVID-19 patients admitted to a tertiary hospital. Method(s): This study is a single-centered cross-sectional retrospective study of hospitalized adult COVID-19 patients between March 2020 to May 2022. COVID-19 confirmed patients who met the inclusion criteria with clinical data upon hospitalization are followed up for occurrence of critical illness. The study's primary outcome is determining the demographic profile and clinical course of COVID-19 infection regarding cardiovascular signs and symptoms. Data were retrieved from electronic health records. All outcomes were obtained with standardized data collection forms, and clinical severity was defined based on the National Institute of Health guidelines. Result(s): A total of 1341 hospitalized adult COVID-19 patients were admitted with a mean age of 50.41+/-15.92 years. More males than females account for 60.2% of the total number of patients. Hypertension is the most common comorbidity among COVID-19 patients, comprising 44% of cases, followed by diabetes at 31.9% and dyslipidemia at 11.4%. About 5.4% had coronary artery disease, followed by heart disease 6 (3.6%) and arrhythmia (0.6%). Most COVID-19 patients were smokers 12% and alcoholic beverage drinkers (11.4%). A univariate analysis associated with mortality showed diabetes mellitus (odds ratio 2.7, p = 0.029) and hypertension (odds ratio 3.4, p = 0.11). In the multiple logistic regression analysis, factors' age (OR 1.095, estimate coefficient 0.091, standard error 0.028, p-value <0.05) and admission duration (OR 0.906, estimate coefficient -0.099, standard error 0.028, p-value <0.05) were significantly associated with mortality. Based on the fitted model, older people are more likely to be deceased than younger people. The log odds for mortality increase by 0.091 units for each year. During hospital admission, 24.43% of patients developed acute COVID-19 infection, with an in-hospital casefatality rate of 13.89%. During hospital stay, COVID-19 patients had a significant QTc (.43 +/- 0.04, p'0.001). Patients admitted to Non-ICU had lower QTc (.44 +/- 0.045) compared to ICU patients (.45 +/- .05). Conclusion(s): Myocardial injury and significant cardiovascular risk factors increased mortality among critically-ill COVID-19 patients. Hence, aside from risk factor modification, emphasis on cardiovascular protection should also be considered during treatment for COVID-19.
ABSTRACT
The goal of this research is to determine the impact of the covid-19 outbreak on Peruvian higher education. Surveys were issued to 349 instructors at various institutions to obtain information. As a result of the study's findings, it appears that COVID-19 has a detrimental influence on higher education, running interruptions to teaching and learning, less access to educational and research resources, job losses and increased student debt. However, virtual education has been impeded by limited internet connectivity, a scarcity of computer equipment, and a lack of digital literacy. The study underlines the importance of adopting distance education technology in order to mitigate the consequences of COVID-19 and potential future pandemics on university education. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
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The purpose of the study was to evaluate the variation of air quality parameters: PM10, PM2.5, NO2, and O3 in four districts of Lima-Peru (Carabayllo, San Juan de Lurigancho, Villa María del Triunfo, and Jesús María) in the period 2015-2019 and 2020-2021. Likewise, the ozone variability in the Carabayllo district was modelled. Pollutant concentration data were collected from the National Service of Meteorology and Hydrology of Peru (SENAMHI) from the 4 stations located in the aforementioned districts. The data was processed with the IBM SPSS Statistics v.25 software. A statistically significant decrease was observed between the 2015-2019 and 2020-2021 periods in pollutants PM10, PM2.5, and NO2, in the four monitoring stations, mainly because the country entered in a state of emergency (quarantine due to COVID -19). However, an increase in O3 was observed, attributed to the decrease in NOX concentrations. Finally, the gamma generalized linear model represented 87.6% of the ozone variability in the Carabayllo district, showing a good fit for the field data. © 2022 IEEE.
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Background. There is a lack of data specifically addressing the effects of triple therapy consisting of baricitinib plus remdesivir plus dexamethasone compared to dual therapy with remdesivir plus dexamethasone among patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pneumonia. Methods. This retrospective study enrolled hospitalized adults with SARSCoV-2 receiving supplemental oxygen without invasive mechanical ventilation (IMV) being treated baricitinib (≤10 days) plus remdesivir (≤10 days) plus dexamethasone (≤10 days) or remdesivir (≤10 days) plus dexamethasone (≤10 days). The primary endpoint was 28-day mortality. Secondary objectives of this study were to measure progression to IMV, pulse oximetry (SpO2)/fraction of inspired oxygen (FiO2) from hospitalization to discharge, hospital length of stay (LOS), 14-day mortality, 14-day hospital readmissions, inflammatory markers, and safety outcomes. Results. Among patients receiving supplemental oxygen without IMV, 28-day mortality for triple therapy vs. dual therapy was 20% and 24%, respectively (P=1.000). The effect of triple therapy compared to dual therapy on lung function was demonstrated by a 76% vs. 25% increase in SpO2/FiO2. This benefit must be contextualized by an increased progression to IMV among patients receiving triple therapy compared to dual therapy (10 patients [50%] vs. 7 patients [28%], respectively;P=0.130). The increased incidence of IMV translated to a significantly longer hospital LOS among patients receiving triple therapy compared to dual therapy (26 days vs. 17 days, respectively;P=0.001). Conclusion. In patients receiving supplemental oxygen without IMV for SARSCoV-2, triple therapy was not associated with a clinically meaningful reduction in 28-day mortality when compared to dual therapy.
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Background: In this article, we document how our team of translators, interpreters, technical communicators, and health justice workers is collaborating to (re)design COVID-19-related technical documentation for and with Indigenous language speakers in Gainesville, FL, USA;Oaxaca de Juarez, Mexico;and Quetzaltenango, Guatemala. Literature review: Although (mis)representations of Indigenous communities have been an ongoing issue in and beyond technical communication, the COVID-19 pandemic has brought added attention to how government institutions and other agencies fail to consider the cultural values, languages, and communication practices of Indigenous communities when writing, designing, and sharing technical information. Research questions: 1. How can technical communicators work toward social justice in health through collaborative design with Indigenous language speakers?2. How can technical documentation about COVID-19 be (re)designed alongside members of vulnerable communities to redress oppressive representations while increasing access and usability?Methodology: Through interviews and other participatory design activities conducted with Indigenous language speakers in the US, Guatemala, and Mexico, we illustrate how Western approaches to creating technical documentation, particularly in health-related contexts such as the COVID-19 pandemic, put communities at risk by failing to localize health messaging for Indigenous audiences. We then document our work intended to collaboratively design and translate COVID-19-related technical information alongside those Indigenous language speakers to benefit Indigenous language speakers in Gainesville and other parts of North Central Florida. Results: Through this discussion, we highlight how technical communicators can collaborate with Indigenous language speakers to create, translate, and share multilingual technical documents that can contribute to social justice efforts by enhancing language access. Conclusion: Through collaborations with Indigenous language speakers, translators, and interpreters, social/health justice projects in technical communication can be combined, localized, and adapted to better serve and represent the diversity of people, languages, and cultures that continue to increase in our world. IEEE
ABSTRACT
At all educational levels, it is necessary to have a teacher training to teach, except at the university. The crisis of professionalism in the university teaching function is worsening, it constitutes an unresolved challenge. The objective of the study is to understand the predominant identity representations that define the performance of the university teacher in a situation of digital society and new normality. Fifteen university professors participated, participants of the program identities in times of pandemic, of the Peruvian Network of Universities. The results show that the abrupt change in university training and academic-organizational processes, caused by COVID-19, by demanding new functions and competencies in the action of university teaching, generate a permanent tension that overwhelms, complicates and undermines the dichotomous professional identity between what is, and what should be, putting at risk the professional legitimacy of the teacher and the social value of the university. © 2021 Maulana Malik Ibrahim State Islamic University of Malang. All rights reserved.